{
"type": "comprehensive medical infographic",
"style": "highly detailed 3D medical illustration, clinical white background, clean typography",
"header": {
"title_cn": "{argument name="main title" default="痛风诞生的因果链"}",
"title_en": "{argument name="english title" default="THE CAUSAL CHAIN OF GOUT"}",
"subtitle": "Pain is not the beginning. Metabolic imbalance is.",
"top_right_sequence": {
"count": 6,
"labels": [
"Metabolism",
"Transport",
"Crystallization",
"Immunity",
"Inflammation",
"Damage"
]
}
},
"centerpiece": {
"description": "{argument name="central figure" default="transparent anatomical human body showing liver,
kidneys,
and vascular system"}",
"details": "pathway highlighted in {argument name="highlight color" default="glowing red"} descending to the foot"
},
"layout": {
"left_column": [
{
"id": "01",
"title": "Purine Sources",
"elements": 6,
"labels": [
"Red meat",
"Organ meats",
"Seafood",
"Beer",
"Endogenous",
"Fructose"
]
},
{
"id": "02",
"title": "Uric Acid Production",
"elements": 2,
"labels": [
"Chemical pathway",
"Liver"
]
},
{
"id": "03",
"title": "Renal & Intestinal Excretion",
"elements": 2,
"labels": [
"Kidney nephron",
"Intestines"
]
},
{
"id": "04",
"title": "Hyperuricemia",
"elements": 2,
"labels": [
"Blood vial",
"Solubility graph"
]
}
],
"center_overlay": [
{
"id": "05",
"title": "Crystal Physics",
"elements": 3,
"labels": [
"Supersaturation beaker",
"Precipitation beaker",
"Molecular structure"
]
},
{
"id": "06",
"title": "Joint Deposition & Local Environment",
"elements": 1,
"labels": [
"First MTP joint cross-section"
]
}
],
"right_column": [
{
"id": "07",
"title": "Immune Inflammatory Cascade",
"elements": 4,
"labels": [
"Macrophage",
"Inflammasome",
"Neutrophil",
"Cytokines"
]
},
{
"id": "08",
"title": "Acute Gout Flare",
"elements": 1,
"labels": [
"Inflamed foot"
]
},
{
"id": "09",
"title": "Chronic Structural Damage",
"elements": 1,
"labels": [
"Bone erosion joint"
]
},
{
"id": "10",
"title": "Tophus Formation",
"elements": 2,
"labels": [
"Hand tophi",
"Foot tophi"
]
},
{
"id": "11",
"title": "Beyond the Joint",
"elements": 2,
"labels": [
"Kidney stones",
"Systemic burden"
]
}
],
"bottom_row": [
{
"id": "12",
"title": "Pain Is the Final Signal",
"elements": 7,
"labels": [
"Increased Purine",
"Overproduction",
"Reduced Excretion",
"Hyperuricemia",
"Crystal Formation",
"Immune Activation",
"Man in pain"
]
}
]
},
"theme": "{argument name="disease focus" default="gout and uric acid crystallization"}"
}
